Hi Sai!
No, you don't have to create other receiver determinations.
In your existing receiver determinarion defined for your Async response sender system/interface just set condition like I showed above and set business conponent with mail receiver channel for that condition. And set "Ignore" option if the receiver not found in receiver determination settings.
Thus, if your response async message doesn't contain value "Success" in element defined in XPath expression the message is routed to receiver with mail communication channel. In other case message is dropped and no further processing takes place.
Regards, Evgeniy.