Hello Pramod,
To the best of my knowledge and my experience with similar information pop-ups, we can go ahead. See one such pop-up with message below, I get during use of few enhancement objects, which I always work with. "Carry out repairs in non-original system only if they are urgent".
When you click on the ? help you will get below information in your case .
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Diagnosis
The object being edited is in a namespace reserved for objects belonging to SAP or another software producer.
This system is supplied with this namespace.
System Response
The function continues.
Procedure
Only perform urgent repairs and only after consulting with or on instruction from the owner of the namespace.
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In short, we work beyond these messages, which initially used to contact BASIS people for risk assessment. You also may do the same. My personal opinion is these are not critical because of the message in the System Response above: "The function continues."
Also you can test well in Dev environment and assess yourself.
Good luck
KJogeswaraRao